RESTYLANE AND PERLANE

Restylane® and Perlane® are cosmetic dermal fillers that replace lost volume and restore youthful contours to the skin to smooth away moderate to severe facial wrinkles and folds, such as the lines from your nose to the corners of your mouth (nasolabial folds). Restylane is the world’s most used, most studied dermal filler, and has been used in over 70 countries and in more than 1.4 million treatments in the U.S.

Restylane® and Perlane®: Long-lasting for about six months

If you’re considering treatment for your facial wrinkles and folds, we invite you to learn important facts about Restylane® and Perlane®, including how they provide structural support and lift to nasolabial folds. In this section, you’ll learn where Restylane or Perlane can be used and see examples of how either treatment can help you reach your goal of a more youthful appearance. The procedure is non-surgical, and its effects are virtually instantaneous.

Restylane® products are cosmetic dermal fillers that replace lost volume and restore youthful contours to the skin to smooth away moderate to severe facial wrinkles and folds, such as the lines from your nose to the corners of your mouth (nasolabial folds).

Restylane and Perlane® are made of hyaluronic acid. In the human body, natural hyaluronic acid provides volume and fullness to the skin. The hyaluronic acid in Restylane and Perlane has been modified slightly to last longer than the body’s hyaluronic acid. The hyaluronic acid in Restylane and Perlane is produced by a biotechnical process.

Restylane and Perlane are hydrophilic or “water loving.” The hydrophilic nature of these hyaluronic acid molecules and their three dimensional structure allows them to bind many times their own weight in water. As hyaluronic acid begins to degrade, each molecule binds to more water which helps to maintain its volume for about six months.

Restylane and Perlane contain no animal proteins. This limits any risk of animal-based disease transmission or allergic reactions. Restylane and Perlane contain trace amounts of gram-positive bacterial proteins and are contraindicated for patients with a history of allergies to such material. No allergy testing is required before use.

Restylane® and Perlane® are FDA-approved for the treatment of moderate to severe facial wrinkles and folds, such as the lines from your nose to the corners of your mouth (nasolabial folds). Restylane has been used in over 70 countries and in more than 1.4 million treatments in the U.S. Perlane has been used by dermatologists and plastic surgeons worldwide since 2000.

Restylane® and Perlane® require no pre-testing. Before being treated with Restylane and Perlane you should take a few precautions. Prior to treatment, avoid using aspirin, non-steroidal anti-inflammatory medications, St. John’s wort, or high doses of Vitamin E supplements. Also, if you have previously suffered from facial cold sores, discuss this with your doctor, who may prescribe a medication to minimize recurrence.

Restylane and Perlane are injected directly into the skin in small amounts by an ultrafine needle. As with all injections, some patients may experience discomfort. To increase your comfort, your doctor will assess your need for pain management and determine what technique is right for you.

Restylane® and Perlane® are approved for the treatment of moderate to severe facial wrinkles and folds, such as the lines from your nose to the corners of your mouth (nasolabial folds).

Restylane® and Perlane® have well-defined safety profiles. Restylane has been used in over 1.4 million treatments in the U.S. and is available in more than 70 countries. It is the most studied cosmetic dermal filler in the world with dozens of publications in the medical literature. Clinical studies have shown no significant differences in the safety of Restylane and Perlane.

After your treatment with Restylane® or Perlane®, you may have some swelling, redness, pain, bruising, and tenderness. This will normally last less than seven days.

Restylane® and Perlane® are Different from Botox® Cosmetic

Restylane® and Perlane® are cosmetic dermal fillers injected into the skin to smooth facial wrinkles and folds, such as the lines from your nose to the corners of your mouth (nasolabial folds). In contrast, Botox® Cosmetic is a drug that blocks nerve transmission and relaxes the muscles that cause frown lines between your eyebrows.

Restylane® and Perlane® are Different from Animal-Based Hyaluronic Acids and Bovine Collagen Products

Restylane® and Perlane® contain no animal proteins. This limits any risk of animal-based disease transmission or allergic reactions. Restylane and Perlane do not require an allergy test and can be administered immediately, so there is no waiting for treatments. Restylane and Perlane contain trace amounts of gram-positive bacterial proteins and are contraindicated for patients with a history of allergies to such material.